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Single doses of antacid (magnesium hydroxide/aluminum hydroxide) did not affect the bioavailability of VIAGRA. Although the interaction between other protease inhibitors and sildenafil has not been studied, their concomitant use is expected to increase sildenafil levels. Cimetidine (800 mg), a nonspecific CYP inhibitor, caused a 56% increase in plasma sildenafil concentrations when co-administered with VIAGRA (50 mg) to healthy volunteers. In addition, N-desmethyl metabolite AUC and Cmax values significantly increased by 200% and 79%, respectively in subjects with severe renal impairment compared to subjects with normal renal function. The mean profiles of the change from baseline in standing systolic blood pressure in subjects treated with doxazosin in combination with 100 mg VIAGRA or matching placebo are shown in Figure 4.

The highest available Viagra dosage is 100 mg, but that doesn’t mean 100 mg is suitable for you. When it comes to medication, more isn't always better (or more effective). Like any medication, Viagra comes with potential risks, side effects, and contraindications.

When hypertension occurs in the lungs, the heart must work harder to pump enough blood through the lungs. Sildenafil works on the PDE5 enzyme in the lungs to relax the blood vessels. This will increase the supply of blood to the lungs and reduce the workload of the heart. Rarely, sudden decreased vision, including permanent blindness, in one or both eyes (NAION) may occur.

If you feel that the effect of VIAGRA is too strong or too weak, talk to your doctor or pharmacist. You should take VIAGRA about one hour before you plan to have sex. You should be aware of how you react to VIAGRA before you drive or use machinery. Our doctors review all orders and issue new or repeat prescriptions online direct to our pharmacy.

The European Medicines Agency has waived the obligation to submit the results of studies with VIAGRA in all subsets of the paediatric population for the treatment of erectile dysfunction. Sildenafil (50 mg) did not potentiate the hypotensive effects of alcohol in healthy volunteers with mean maximum blood alcohol levels of 80 mg/dl. A medical history and physical examination should be undertaken to diagnose erectile dysfunction and determine potential underlying causes, before pharmacological treatment is considered. In addition, initiation of sildenafil at a dose of 25 mg should be considered (see sections 4.4 and 4.5). VIAGRA is indicated in adult men with erectile dysfunction, which is the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance.

Even though generic sildenafil is unbranded, it is still an effective treatment for ED and works in the same way as Viagra. If you are interested in using this popular ED treatment, you can buy Spedra from The Independent Pharmacy. In clinical trials, Viagra provides effective treatment for erectile dysfunction in about 80% of men, whereas Spedra only provides effective treatment to about 60% of men. As with all ED medication, there is a small chance that there will be little or no effect. This is particularly true if it is one of the first times you are using this medicine, so we generally advise that you try your Spedra dose at least eight times before switching to another dosage or medicine. It is usually recommended that you start by taking the 100mg tablets.

Once the effects of Viagra have worn off, it’s likely the side effects will too. If you are worried about the side effects you are experiencing, contact your doctor for advice. Several factors can affect how long Viagra lasts including, your age, health, diet, and alcohol consumption. It is noteworthy that before the invention of Viagra, there were no effective and at the same time safe ways to deal with erectile dysfunction. All of them were fraught with serious consequences for the body of men and mostly had a narcotic character.

Avoid consumption of alcohol as it may impair your ability to get an erection. Taking SILDENAFIL after a heavy meal might take longer time for the medicine to work